C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 513/04 (2006.01) A61K 31/415 (2006.01) A61K 31/426 (2006.01) A61K 31/429 (2006.01) A61K 31/433 (2006.01) A61K 31/4402 (2006.01) A61K 31/505 (2006.01) C07D 213/75 (2006.01) C07D 231/40 (2006.01) C07D 239/42 (2006.01) C07D 239/84 (2006.01) C07D 241/20 (2006.01) C07D 277/46 (2006.01) C07D 277/82 (2006.01) C07D 285/135 (2006.01)
Patent
CA 2623045
The present invention provides compounds of the formula (I), which are activators of glucokinase activity and, thus, may be employed as therapeutic agents for the treatment of glucokinase mediated conditions. Accordingly, the compounds of formula (I) may be employed for the prevention and the treatment of impaired glucose tolerance, type 2 diabetes and obesity.
La présente invention concerne des composés de formule (I), qui sont des agents activants de l'activité de la glucokinase et qui, ainsi, peuvent être employés en tant qu'agents thérapeutiques dans le traitement d'états pathologique faisant intervenir la glucokinase. Ainsi, les composés de formule (I) peuvent être employés dans le traitement prophylactique et thérapeutique d'une déficience de la tolérance au glucose, du diabète de type 2 et de l'obésité.
Bebernitz Gregory Raymond
Kirman Louise
Fetherstonhaugh & Co.
Novartis Ag
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