Sulfonamide derivatives as ppar modulators

Details Sulfonamide derivatives as ppar modulators Sulfonamide derivatives as ppar modulators

C - Chemistry, Metallurgy

07

D

C07D 333/62 (2006.01) A61K 31/00 (2006.01) A61K 45/06 (2006.01) C07C 311/13 (2006.01) C07C 311/16 (2006.01) C07C 311/17 (2006.01) C07C 311/19 (2006.01) C07C 311/29 (2006.01) C07C 317/14 (2006.01) C07C 323/49 (2006.01) C07C 323/52 (2006.01) C07D 207/08 (2006.01) C07D 209/08 (2006.01) C07D 209/48 (2006.01) C07D 213/64 (2006.01) C07D 213/71 (2006.01) C07D 213/74 (2006.01) C07D 215/36 (2006.01) C07D 231/12 (2006.01) C07D 231/18 (2006.01) C07D 263/32 (2006.01) C07D 271/12 (2006.01) C07D 277/36 (2006.01) C07D 307

Patent

CA 2512883

The present invention is directed to a compound of Formula (I):, and pharmaceutically acceptable salts, solvates, hydrates or stereoisomers thereof, which are useful in treating or preventing disorders mediated by a peroxisome proliferator activated receptor (PPAR) such as syndrome X, type II diabetes, hyperglycemia, hyperlipidemia, obesity, coagaulopathy, hypertension, arteriosclerosis, and other disorders related to syndrome X and cardiovascular diseases.

Cette invention se rapporte à un composé représenté par la formule (I), et à des sels, solvates, hydrates ou stéréo-isomères de ce composé, acceptables sur le plan pharmaceutique, qui sont utiles pour traiter ou prévenir les affections médiées par le récepteur activé de la prolifération des peroxysomes (PPAR), telles que le syndrome X, le diabète non insulino-dépendant, l'hyperglycémie, l'hyperlipidémie, l'obésité, les troubles de la coagulation, l'hypertension, l'artériosclérose, et d'autres affections liées au syndrome X et aux maladies cardio-vasculaires .

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