C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 311/27 (2006.01) A61K 31/16 (2006.01) A61P 43/00 (2006.01) C07D 209/08 (2006.01) C07D 209/12 (2006.01) C07D 235/06 (2006.01) C07D 317/58 (2006.01) C07D 407/12 (2006.01)
Patent
CA 2355902
This invention relates to sulfonamide derivatives of formula (Ia) (in which R is -CH(R2)Ar1 or -CH(R2)CH=CHAr1, and the other variables are as defined in the claims) that are inhibitors of procollagen C-proteinase, pharmacological compositions containing them, their use, intermediates and methods for preparing these compounds.
L'invention a trait à des dérivés de sulfonamide représentés par la formule Ia (dans laquelle R est -CH(R?2¿)Ar1 ou -CH(R?2¿)CH=CHAr?1¿, les autres variables étant définies dans les revendications) qui constituent des inhibiteurs de procollagène C-protéinase, à des compositions pharmaceutiques contenant ceux-ci, à leur utilisation, à des produits intermédiaires et à des procédés de préparation de ces composés.
Billedeau Roland Joseph
Broka Chris Allen
Campbell Jeffrey Allen
Chen Jian Jeffrey
Dankwardt Sharon Marie
F. Hoffmann-La Roche Ag
Gowling Lafleur Henderson Llp
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