Sulfonamide substituted xanthine derivatives for use as...

C - Chemistry – Metallurgy – 07 – D

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C07D 473/04 (2006.01) A61K 31/52 (2006.01) A61P 3/10 (2006.01) C07D 473/06 (2006.01) C07D 473/08 (2006.01)

Patent

CA 2514472

The present invention is concerned with sulfonamide substituted xanthine derivatives of formula (I) or a pharmaceutically acceptable salts or prodrugs thereof, wherein R1, R2 and R3 are as defined in the specification. Compounds of formula (I) and pharmaceutically acceptable salts or prodrugs thereof show activity as modulators of gluconeogenesis.

La présente invention porte sur des dérivés de xanthine substitués par des sulfonamides de formule (I) ou sur des sels acceptables d'un point de vue pharmaceutique ou des promédicaments de ceux-ci. Dans cette formule, R?1¿, R?2¿ et R?3¿ sont tels que définis dans le descriptif. L'invention porte également sur des composés de formule (I) et sur des sels acceptables d'un point de vue pharmaceutique ou des promédicaments de ceux-ci qui ont une activité de modulateurs de la gluconéogenèse.

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