Sulfonamide-thiazolpyridine derivatives as glucokinase...

C - Chemistry – Metallurgy – 07 – D

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C07D 513/04 (2006.01) A61K 31/429 (2006.01)

Patent

CA 2560689

The present invention provides compounds of the formula (I), which are activators of glucokinase activity and, thus, may be employed as therapeutic agents for the treatment of glucokinase mediated conditions. Accordingly, the compounds of formula (I) may be employed for the prevention and the treatment of impaired glucose tolerance, Type 2 diabetes and obesity.

La présente invention concerne des composés de formule (I) qui sont des activateurs de l'activité de la glucokinase et peuvent ainsi être employés comme agents thérapeutiques pour le traitement d'états pathologiques médiés par la glucokinase. En conséquence, les composés de formule (I) peuvent être employés pour prévenir et traiter la mauvaise tolérance au glucose, le diabète de type 2 et l'obésité.

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