Sulfonamides as zap-70 inhibitors

Details Sulfonamides as zap-70 inhibitors Sulfonamides as zap-70 inhibitors

C - Chemistry, Metallurgy

07

D

C07D 239/48 (2006.01) A61K 31/505 (2006.01) A61K 31/506 (2006.01) A61K 31/5377 (2006.01) A61K 31/538 (2006.01) A61P 37/06 (2006.01) A61P 37/08 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 407/12 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2717529

The invention relates to compounds of formula (I), wherein R1 to R9 and R14a have the meaning as cited in the description and the claims. Said compounds are useful as inhibitors of ZAP-70 for the treatment or prophylaxis of immunological, inflammatory, autoimmune, allergic disorders, and immuno logically-mediated diseases. The invention also relates to pharmaceutical compositions including said compounds, the preparation of such compounds as well as the use as medicaments.

L'invention porte sur des composés de formule (I), dans laquelle R1 à R9 et R4a ont la signification telle qu'énoncée dans la description et les revendications. Lesdits composés sont utiles en tant qu'inhibiteurs de ZAP-70 pour le traitement ou la prophylaxie de troubles immunologiques, inflammatoires, auto-immuns, allergiques et de maladies à médiation immunologique. L'invention porte également sur des compositions pharmaceutiques comprenant lesdits composés, sur la préparation de tels composés ainsi que sur leur utilisation en tant que médicaments.

Affiliated with

Also associated with

Rating

Sulfonamides as zap-70 inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Sulfonamides as zap-70 inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Sulfonamides as zap-70 inhibitors will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1676321