Sulfonamidocarboxamides

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 211/34 (2006.01) A61K 31/435 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) A61K 31/675 (2006.01) A61K 38/05 (2006.01) C07C 229/28 (2006.01) C07D 211/26 (2006.01) C07D 265/30 (2006.01) C07D 401/12 (2006.01) C07D 413/12 (2006.01) C07F 9/59 (2006.01) C07K 5/06 (2006.01) C07K 5/068 (2006.01) C07K 5/072 (2006.01) C07K 5/078 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2089972

The novel sulphonamidocarboxamides of the formula (see fig. I) wherein A, M, Q, X and Y have the significance given in the description, as well as hydrates or solvates thereof inhibit thrombin-induced blood platelet aggregation and clotting of fibrinogen in plasma. They are manufactured by amidination of a cyclic amino group standing for grouping X or by C(O)N(Q) amide formation.

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