B - Operations – Transporting – 01 – J
Patent
B - Operations, Transporting
01
J
252/23, 530/3.2,
B01J 20/32 (2006.01) B01D 15/08 (2006.01)
Patent
CA 1291593
SULFONIC DERIVATIVES OF ACYLATED POLYETHYLENEIMINE BONDED PHASE SILICA PRODUCTS ABSTRACT OF THE DISCLOSURE Sulfonic derivatives of N-acylated covalently bound, non-crosslinked polyethyleneimine bonded phase silicas of the formula: Image wherein ? is the backbone of a silica gel or glass, n is an integer such that the polyethyleneiminopropyl silane group has an average molecular weight of from about 400 to about 1800; q is an integer of zero or one; R is selected from the group consisting of hydrogen, Image or Image where x is an integer of 1 or 2 and m is an integer of zero or 1; when R is hydrogen or Image then R1 is Image where p is an integer of zero ox 1, and when R is Image then R1 is selected from the group consisting of hydrogen or Image where y is an integer of zero or 1, are especially useful as solid phases for the purification and separation of proteins having isoelectric points of below about 5.
528080
Nau David R.
Ramsden Hugh E.
Mallinckrodt Baker Inc.
Osler Hoskin & Harcourt Llp
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