Sulfonic derivatives of acylated polyethylenimine bonded...

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252/23, 530/3.2,

B01J 20/32 (2006.01) B01D 15/08 (2006.01)

Patent

CA 1291593

SULFONIC DERIVATIVES OF ACYLATED POLYETHYLENEIMINE BONDED PHASE SILICA PRODUCTS ABSTRACT OF THE DISCLOSURE Sulfonic derivatives of N-acylated covalently bound, non-crosslinked polyethyleneimine bonded phase silicas of the formula: Image wherein ? is the backbone of a silica gel or glass, n is an integer such that the polyethyleneiminopropyl silane group has an average molecular weight of from about 400 to about 1800; q is an integer of zero or one; R is selected from the group consisting of hydrogen, Image or Image where x is an integer of 1 or 2 and m is an integer of zero or 1; when R is hydrogen or Image then R1 is Image where p is an integer of zero ox 1, and when R is Image then R1 is selected from the group consisting of hydrogen or Image where y is an integer of zero or 1, are especially useful as solid phases for the purification and separation of proteins having isoelectric points of below about 5.

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