Sulfonyl aryl triazoles as anti-inflammatory/analgesic agents

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 249/08 (2006.01) A61K 31/4196 (2006.01) A61P 29/00 (2006.01) C07D 401/04 (2006.01) C07D 405/04 (2006.01)

Patent

CA 2390181

-59- The present invention relates to compounds of the formula <SEE FORMULA 1> wherein m, R1, R3, R4, and R5 are defined as in the specification, to pharmaceutical compositions containing them and to their medicinal use. The compounds of the invention are useful in the treatment or alleviation of inflammation and other inflammation associated disorders, such as osteoarthritis, rheumatoid arthritis, colon cancer and Alzheimer's disease, in mammals (preferably humans, dogs, cats and livestock).

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