Sulfonyl-substituted 6-membered ring derivative

Details Sulfonyl-substituted 6-membered ring derivative Sulfonyl-substituted 6-membered ring derivative

C - Chemistry, Metallurgy

07

C

C07C 317/44 (2006.01) A61K 31/4164 (2006.01) A61K 31/426 (2006.01) A61K 31/433 (2006.01) A61K 31/44 (2006.01) A61K 31/4439 (2006.01) A61K 31/444 (2006.01) A61K 31/445 (2006.01) A61K 31/497 (2006.01) A61K 31/505 (2006.01) A61K 31/506 (2006.01) A61P 1/04 (2006.01) A61P 1/16 (2006.01) A61P 1/18 (2006.01) A61P 3/04 (2006.01) A61P 3/06 (2006.01) A61P 3/10 (2006.01) A61P 3/12 (2006.01) A61P 5/00 (2006.01) A61P 9/00 (2006.01) A61P 9/04 (2006.01) A61P 9/10 (2006.01) A61P 9/12 (2006.01) A61P 11/00 (2006.01) A61P 13/

Patent

CA 2707447

A compound that is useful as an agent in the prevention and treatment of circulatory system, nervous system, metabolic, reproductive system, and gastrointestinal diseases. Formula (I) is a compound represented by the following: [structure 1] [wherein, Z represents formula (II-1), (II-2), or (II-3), [structure 1] m and n are 0, 1, or 2, Y represents CR3 or N, R1 represents a C1-6 alkyl, C3-8 cycloalkyl, etc., R2 represents phenyl or a heteroaryl, etc., R3 and R4 each independently represent a hydrogen atom, a C1-6 alkyl, etc., M1, M2, M3, and M4 each independently represent a hydrogen atom, a C1-6 alkyl, etc.]

L'invention concerne un composé utilisé comme agent dans la prévention et le traitement de maladies du système circulatoire, du système nerveux, métaboliques, du système reproducteur et gastro-intestinales. La formule (I) représente un composé comme il suit: [structure 1] [dans laquelle Z représente la formule (II-1), (II-2) ou (II-3), [structure 1] m et n sont 0, 1 ou 2, Y représente CR3 ou N, R1 représente un alkyle C1-6, un cycloalkyle C3-8, etc., R2 représente phényle ou un hétéroaryle, etc., R3 et R4 représentent chacun indépendamment un atome d'hydrogène, un alkyle C1-6, etc., et M1, M2, M3 et M4 représentent chacun indépendamment un atome d'hydrogène, un alkyle C1-6, etc.].

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