Sulfonylurea derivatives

C - Chemistry – Metallurgy – 07 – C

Patent

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167/207, 167/266

C07C 311/60 (2006.01) C07D 317/62 (2006.01) C07D 319/18 (2006.01)

Patent

CA 1281333

ABSTRACT OF THE DISCLOSURE This invention provides sulfonamide derivatives of formula (I): Image (I) in which A is -O-, ?CH3, -CH2-, -CH2CH2-, or -CH2O-; D is -CH2- or -O-; provided that neither A nor D can be -O- unless both A and D are -O-; R1 is hydrogen or halo, and R2 is halo or trifluoromethyl. These derivatives are useful in the treatment of susceptible neoplasms in warm-blooded animals.

518656

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