Sulfoximine derivatives as p38 map kinase inhibitors

Details Sulfoximine derivatives as p38 map kinase inhibitors Sulfoximine derivatives as p38 map kinase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 417/04 (2006.01) A61K 31/427 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2633083

The present invention relates to novel compounds of general formula (I), their tautomeric forms, novel intermediates involved in their synthesis, their pharmaceutically acceptable salts and pharmaceutical compositions containing them. The present invention also relates to a process of preparing compounds of general formula (I), their regioisomers, their tautomeric forms, their pharmaceutically acceptable salts and pharmaceutical compositions containing them, and novel intermediates involved in their synthesis. The compounds are useful as p38 MAP kinase inhibitors. (see formula I)

L'invention se rapporte à de nouveaux composés de la formule générale (I), à leurs régioisomères, à leurs formes tautomères et à de nouveaux intermédiaires intervenant dans leur synthèse, à leurs sels pharmaceutiquement acceptables et à des compositions pharmaceutiques les contenant. L'invention concerne également un procédé de préparation de composés de la formule générale (I), de leurs régioisomères, de leurs formes tautomères, de leurs sels pharmaceutiquement acceptables, de compositions pharmaceutiques les contenant et de nouveaux intermédiaires intervenant dans leur synthèse.

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