Sulfur-containing fused pyrimidine derivatives, their...

Details Sulfur-containing fused pyrimidine derivatives, their... Sulfur-containing fused pyrimidine derivatives, their...

C - Chemistry, Metallurgy

07

D

167/208, 260/242

C07D 513/04 (2006.01) A61K 31/54 (2006.01) A61K 31/55 (2006.01)

Patent

CA 2019369

Disclosed is a compound represented by the formula (I) or a salt thereof: Image wherein R1 represents an aliphatic hydrocarbon, aralkyl or aryl group which may be substituted; R2 represents hydrogen, an aliphatic hydrocarbon group having one or more substituents, an aryl group which may be substituted, an amino group which may be substituted, a formyl group; a nitro group or a halogeno group; A represents a divalent hydrocarbon chain of 2 to 4 carbon atoms which may be substituted; and m represents an integer of 0 to 2, which is useful for treatment and prevention of diseases induced by abnormalities in regulation of reactions in vivo mediated through endothelin or interleukin 1, and of immune diseases and inflammatory diseases.

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