Sulphamoylthiophenes, a process for their preparation and...

C - Chemistry – Metallurgy – 07 – D

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C07D 409/12 (2006.01) A61K 31/47 (2006.01)

Patent

CA 2019738

Abstract Sulphamoylthiophenes of the formula Image I, in which Y denotes O or S, A denotes a single bond or a straight-chain or branched alkylene group having 1 - 5 carbon atoms, R1 denotes methyl or trifluoromethyl and R2 denotes hydrogen or a group COOH or COOR3, in which R3 represents (C1-C4)-alkyl, and, in the case in which R2 denotes a group COOH, their pharmaceutically tolerable salts, a process for their preparation, pharmaceutical preparations which contain these compounds and their use in medicaments as leuko- triene antagonists for the treatment of asthma and allergies.

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