A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
167/104, 167/199
A61K 45/08 (2006.01) A61K 31/13 (2006.01) A61K 31/70 (2006.01) A61K 35/39 (2006.01) C08B 37/00 (2006.01) C08B 37/08 (2006.01) C08B 37/10 (2006.01) C12P 19/00 (2006.01)
Patent
CA 2026036
The present invention relates to sulphated glycosamino glycuronan with antithrombotic activity consisting essentially of salts of dermatan sulphate, chondroitin sulphate and heparan sulphate, characterized by a) an average molecular weight between 4000 and 8000 daltons; b) a nitrogen content between 2.4 and 3.0%; c) a sulphur content between 7.5 and 9.5%; d) a sodium content between 9 and 11%; e) a dermatan sulphate content between 5 and 25%; f) a chondroitin sulphate content less than 9%; g) an anti-Xa activity between 11 and 20 u/mg; and h) an antithrombin III dependent antithrombin activity of less than 1 u/mg.
Meuleman Dirk G.
Moelker Huibert C. T.
Sanders Adrianus L. M.
Van Dedem Gijsbert W. K.
Van Houdenhoven Francois E. A.
Akzo N.v.
Fetherstonhaugh & Co.
N.v. Organon
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