Sulphonamides

Details Sulphonamides Sulphonamides

C - Chemistry, Metallurgy

07

D

260/247.1, 260/2

C07D 207/09 (2006.01) C07D 211/28 (2006.01) C07D 295/12 (2006.01) C07D 295/13 (2006.01)

Patent

CA 1173443

ABSTRACT Compounds of the formula (I) as antiarrhthmic agents and salts thereof: Image (I) wherein: A is a bond, -CH2- or -CH=CH-; R2 is hydrogen and R1 is selected from C1-4 alkyl, hydroxyl, C1-4 alkoxy, C1-4 alkanoyloxy, hydrogen, halogen, nitro, cyano, and amino optionally substituted by one or two C1-4 alkyl groups or by C1-4 alkanoyl; R4 is C1-4 alkyl, hydroxy, C1-4 alkoxy, C1-4 alkanoyloxy or nitrato; R2N is 1-piperidyl, morpholino or 4-methyl-1-piperazyl, optionally substituted by one or two methyl groups in the 2-, 4- or 6- positions as apt, or 1-pyrrolidyl substituted by one or two methyl groups. m is 0 or 1; and n is 0 to 3 a process for their preparation and compositions containing them.

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