Sulphones which modulate the action of gamma-secretase

Details Sulphones which modulate the action of gamma-secretase Sulphones which modulate the action of gamma-secretase

C - Chemistry, Metallurgy

07

C

C07C 317/46 (2006.01) C07C 317/14 (2006.01) C07C 317/20 (2006.01) C07C 317/24 (2006.01) C07C 317/30 (2006.01) C07D 207/12 (2006.01) C07D 207/24 (2006.01) C07D 207/27 (2006.01) C07D 207/404 (2006.01) C07D 211/18 (2006.01) C07D 211/42 (2006.01) C07D 211/46 (2006.01) C07D 211/54 (2006.01) C07D 211/60 (2006.01) C07D 211/62 (2006.01) C07D 211/72 (2006.01) C07D 211/78 (2006.01) C07D 213/40 (2006.01) C07D 213/64 (2006.01) C07D 213/65 (2006.01) C07D 217/20 (2006.01) C07D 233/32 (2006.01) C07D 233/40 (2006.01) C07D

Patent

CA 2442882

Novel sulphones of Formula I are disclosed: wherein A completes a 4-7 membered ring optionally comprising up to two heteroatoms. The compounds modulate the action of g-secretase and are therefore useful in the treatment or prevention of Alzheimer's disease.

L'invention concerne des nouveaux sulfones de formule I: dans laquelle A désigne un cycle à 4-7 chaînons, comprenant éventuellement jusqu'à deux hétéroatomes. Les composés modulent l'action de la g-sécrétase et sont, par conséquent, utiles dans le traitement ou la prévention de la maladie d'Alzheimer.

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