Super-antigen fusion proteins and the use thereof

Details Super-antigen fusion proteins and the use thereof Super-antigen fusion proteins and the use thereof

C - Chemistry, Metallurgy

12

N

C12N 15/50 (2006.01) A61K 38/16 (2006.01) A61K 39/104 (2006.01) A61K 39/215 (2006.01) A61P 31/14 (2006.01) C07K 14/165 (2006.01) C07K 14/21 (2006.01) C07K 19/00 (2006.01) C12N 15/31 (2006.01) C12N 15/62 (2006.01)

Patent

CA 2512515

The present invention relates to a super-antigen fusion protein, comprising: a peptide fragment encoding a partial SARS E2 spike protein; and a translocating peptide fragment for transporting a protein into a cell and translocating the protein in cytosol; wherein, the amino acid of the peptide fragment encoding the partial SARS E2 spike protein includes SEQ ID NO.1, SEQ ID NO.2, SEQ ID NO.3 or SEQ ID NO.4. The present invention further relates to DNA sequences encoding the partial SARS E2 spike protein includes SEQ ID NO.5, SEQ ID NO.6, SEQ ID NO.7, or SEQ ID NO.8; wherein the DNA sequences are able to express specific proteins in an E. Coli expression system.

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