Supercritical hydrogenation

C - Chemistry – Metallurgy – 07 – B

Patent

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Details

C07B 35/02 (2006.01) A61K 31/424 (2006.01) A61P 25/00 (2006.01) C07B 43/04 (2006.01)

Patent

CA 2442926

The present invention relates to a method of carrying out hydrogenation of a substrate in the presence of a supercritical fluid such that more than one phase is present in the reaction medium. The reaction is performed under continuous conditions. The process leads to improved yields of the desired hydrogenated product. The process also enables the selective formation of a particular product where the formation of more than one product is possible.

L'invention concerne un procédé d'hydrogénation de substrat en présence de fluide supercritique, visant à assurer la présence de plusieurs phases dans le milieu de réaction. La réaction est soumise à des conditions continues. On améliore ainsi le rendement relatif à l'élaboration des produits hydrogénés. En outre, ce procédé permet d'engager sélectivement l'élaboration d'un produit spécifique lorsque le processus peut déboucher sur la réalisation de plusieurs produits.

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