Superoxide dismutase as a vaccine antigen

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/395 (2006.01) A61K 31/70 (2006.01) A61K 31/7088 (2006.01) A61K 38/44 (2006.01) A61K 39/02 (2006.01) A61P 31/04 (2006.01) C12N 9/02 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2341639

Compositions comprising Cu,Zn-Superoxide dismutase (Cu,Zn-SOD), nucleic acid encoding a Cu,Zn-SOD and/or antibody to a Cu,Zn-SOD are described as well as their use as vaccines. Also described are methods for isolation of Cu,Zn-SODs and for preparation of pharmaceutical compositions, preferably for providing or eliciting protective immunity to meningococcal infection in an animal.

L'invention concerne des compositions comprenant une Cu,Zn-superoxyde dismutase (Cu,Zn-SOD), un acide nucléique codant Cu,Zn-SOD et/ou un anticorps dirigé contre Cu,Zn-SOD, de même que l'utilisation de ces compositions en tant que vaccins. L'invention concerne encore des procédés d'isolation de Cu-Zn-superoxyde dismutases et de préparation de compositions pharmaceutiques destinées, de préférence, à apporter ou supprimer une immunité protégeant contre une infection méningococcique, chez un animal.

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