Superporous hydrogels for heavy-duty applications

Details Superporous hydrogels for heavy-duty applications Superporous hydrogels for heavy-duty applications

C - Chemistry, Metallurgy

08

L

C08L 33/14 (2006.01) A61K 47/32 (2006.01) C08F 2/44 (2006.01) C08J 3/24 (2006.01) C08J 9/04 (2006.01)

Patent

CA 2686927

The present invention features modified superporous hydrogels (SPHs) and methods for their formation. The SPHs of the present invention are prepared by careful selection of the hydrophobic/hydrophilic reactive ingredients and by harmonizing the foaming and polymerization reactions, which results in the formation of SPHs having a homogeneous structure and favorable physical and mechanical properties, including swelling, strength, ruggedness, and resiliency The SPHs of the present invention are particularly useful when employed in very harsh swelling environments, such as the low pH environment of the gastric fluid of the stomach, for extended periods of time.

Cette invention concerne des hydrogels superporeux modifiés (SPH) ainsi que des procédés permettant de les fabriquer. Les SPH décrits dans cette invention sont préparés par sélection soigneuse d'ingrédients réactifs hydrophiles/hydrophobes puis par harmonisation du moussage et des réactions de polymérisation, ce qui permet d'aboutir à la formation de SPH présentant une structure homogène ainsi que des propriétés mécaniques et physiques avantageuses, parmi lesquelles le gonflement, la résistance, la robustesse et l'élasticité. Les SPH décrits dans cette invention sont particulièrement utiles dans des environnements de gonflement acides, tels que l'environnement au pH basique du fluide gastrique contenu dans l'estomac, pendant des périodes prolongées.

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