Supplemented and unsupplemented tissue sealants, methods of...

A - Human Necessities – 61 – K

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Details

A61K 38/36 (2006.01) A61F 13/00 (2006.01) A61F 13/02 (2006.01) A61K 38/45 (2006.01) A61K 38/48 (2006.01) A61L 15/32 (2006.01) A61L 15/44 (2006.01) A61L 15/58 (2006.01) A61L 26/00 (2006.01)

Patent

CA 2223889

This invention provides a fibrin sealant bandage or dressing, wherein said fibrin sealant may be supplemented with at least one composition selected from, for example, one or more regulatory compounds, antibody, antimicrobial compositions, analgesics, anticoagulants, antiproliferatives, anti- inflammatory compounds, cytokines, cytotoxins, drugs, growth factors, interferons, hormones, lipids, demineralized bone or bone morphogenetic proteins, cartilage inducing factors, oligonucleotides, polymers, polysaccharides, polypeptides, protease inhibitors, vasoconstrictors or vasodilators, vitamins, minerals, stabilizers and the like. Also disclosed are methods of preparing and/or using the unsupplemented or supplemented fibrin sealant bandage or dressing.

Cette invention se rapporte à un bandage ou pansement d'obturation à base de fibrinogène. Ce produit colmatant la fibrine pouvant être complété par au moins une composition sélectionnée, par exemple, parmi un ou plusieurs composés régulateurs, un anticorps, des compositions antimicrobiennes, des analgésiques, des anticoagulants, des agents antiprolifératifs, des composés anti-inflammatoires, des cytokines, des cytotoxines, des médicaments, des facteurs de croissance, des interférons, des hormones, des lipides, des protéines morphogénétiques osseuses ou d'os déminéralisés, des facteurs d'induction du cartilage, des oligonucléotides, des polymères, des polysaccharides, des polypeptides, des inhibiteurs de protéases, des vasoconstricteurs ou des vasodilatateurs, des vitamines, des minéraux, des stabilisateurs et autres. L'invention se rapporte également à des procédés de préparation et/ou d'utilisation du bandage ou pansement d'obturation à base de fibrinogène, non complété ou complété.

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