A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/48 (2006.01) A61K 9/00 (2006.01) A61K 9/20 (2006.01) A61K 9/28 (2006.01)
Patent
CA 2150019
Supported liquid membrane delivery devices that release a beneficial agent to an aqueous environment following exposure to an environmental trigger. A microporous hydrophobic support membrane at least partially surrounds a beneficial agent-containing hydrophilic formulation. A hydrophobic liquid is held within the microporous support membrane by capillarity and the hydrophobic liquid is substantially permeable to the aqueous environment and the beneficial agent-containing hydrophilic formulation. The entrained hydrophobic liquid becomes substantially permeable to the aqueous environment upon exposure to an environmental trigger such as an enzyme, and the beneficial agent is subsequently released.
Divulgation de dispositifs de libération de liquide retenu dans une membrane support qui libèrent un agent utile dans un milieu aqueux après une exposition à un déclencheur environnemental. Une membrane support hydrophobe microporeuse entoure au moins partiellement un agent utile. Un liquide hydrophobe est retenu dans la membrane support microporeuse par capillarité; ce liquide est essentiellement perméable au milieu aqueux et à la formulation hydrophile contenant l'agent utile. Le liquide hydrophobe entraîné devient essentiellement perméable au milieu aqueux lorsqu'il est exposé à un déclencheur environnemental comme une enzyme, et l'agent utile est ensuite libéré.
Herbig Scott M.
Smith Kelly L.
Van Eikeren Paul
West James B.
Limited Pfizer
Smart & Biggar
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