Suppositories

A - Human Necessities – 61 – K

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167/160, 167/212

A61K 31/545 (2006.01) A61K 9/02 (2006.01)

Patent

CA 1256799

Abstract Suppositories containing as the active substance a therapeutically effective amount of ceftriaxone, a pharma- ceutically compatible salt thereof or a hydrate of one of these compounds, a stabilizer consisting of a mono-, di- or triglyceride of a C12-C18-fatty acid or of a mixture of such glycerides, a potentiator consisting of an aliphatic C2-C18-fatty acid, a mono-, di- or triglyceride of a C2-C12-fatty acid, a partial ester or complete ester of propylene glycol, polyethylene glycol or a carbohydrate with a C2-C12-fatty acid, a pharmaceutically compatible ester or ether thereof or of a mixture of the said potentiators and, if desired, customary therapeutically inert adjuvants for suppositories, and their manufacture are described. These have valuable antimicrobial properties.

472732

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