Suppression of eczematous dermatitis by calcium transport...

A - Human Necessities – 61 – K

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167/119, 167/159

A61K 33/24 (2006.01) A61K 31/28 (2006.01)

Patent

CA 1337927

Treatment of an animal with calcium flux inhibitors results in a decrease in the number of epidermal Langerhans cells and a simulta- neous decrease in the ability to respond to contact sensitizing agents. Also, topical application of calcium flux inhibitors will reduce inflam- mation in patients experiencing delayed-type hypersensitivity reac- tion or atopic eczema. Thus, calcium flux inhibitors represent a new class of therapeutic agents in the treatment of contact dermatitis and eczema.

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