Surface active material, method for producing the same, and...

Details Surface active material, method for producing the same, and... Surface active material, method for producing the same, and...

A - Human Necessities

61

K

167/104

A61K 35/42 (2006.01) A61K 31/00 (2006.01) A61K 38/17 (2006.01)

Patent

CA 1161754

Abstract Surface Active Material, Method for Producing the Same, And Pharmaceutical Composition for Hyaline-Membrane Disease Containing Said Material A surface active material may be produced from the lung tissue of mammals by means of an acetone-treatment procedure as well as an organic solvents mixture-treatment procedure other than the conventional procedures of differential centrifugation, density gradient centrifuga- tion and dialysis. The chemical compostion of the active material has, for example, a phospholipid content of 75.0-95.5%, a neutral lipid content of 1.8-14.0%, a total cholesterol content of 0.0-3.0%, a carbohydrate content of 0.1-1.5% and a protein content of 0.5-5.0%, all based on the dried weight of the material. The pharmaceutical composition containing the surface active material defined as above is usable for clinical treatment of human hyaline- membrane disease.

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