A - Human Necessities – 61 – L
Patent
A - Human Necessities
61
L
A61L 31/00 (2006.01) A61L 27/00 (2006.01) A61L 27/34 (2006.01) A61L 27/58 (2006.01) A61L 31/10 (2006.01) A61L 31/14 (2006.01) B05D 1/28 (2006.01)
Patent
CA 2319216
The invention provides a biodegradable and biocompatible polymer article having a surface wherein a biologically active ligand is provided on said surface in a spatially controlled pattern. The pattern may be formed using a poly(dimethyl siloxane) mould. The biologically active ligand may be attached to the polymer article by a biotin-avidin-biotin linkage.
L'invention concerne un articule de polymère biodégradable et biocompatible présentant une surface sur laquelle un ligand biologiquement actif est disposé selon un motif contrôlé spacialement. Ce motif peut être formé à l'aide d'un moule de poly(diméthyl siloxane). Ce ligand biologiquement actif peut être fixé à l'article de polymère par une liaison biotine-avidine-biotine.
Cannizzaro Scott M.
Langer Robert S.
Patel Nikin
Shakesheff Kevin
Bereskin & Parr
Massachusetts Institute Of Technology
The University Of Nottingham
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