C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/11 (2006.01) A61K 38/16 (2006.01) A61K 39/118 (2006.01) C07K 14/00 (2006.01) C07K 14/295 (2006.01) C07K 16/12 (2006.01) C12Q 1/68 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2294651
The invention relates to the identification of members of a gene family from the human respiratory pathogen Chlamydia pneumoniae, encoding surface exposed membrane proteins of a size of approximately 89-101 kDa and of 56-57 kDa, preferably about 89.6-100.3 kDa and about 56.1 kDa. The invention relates to the novel DNA sequences, the deduced amino acid sequences of the corresponding proteins and the use of the DNA sequences and the proteins in diagnosis of infections caused by C. pneumoniae, in pathology, in epidemiology, and as vaccine components.
L'invention concerne l'identification de membres d'une famille génique issue de l'agent pathogène humain des voies respiratoires, Chlamydia pneumoniae, qui codent des protéines membranaires externes présentant une taille d'environ 89 à 101 kDa et 56 à 57 kDa ou, de préférence, une taille d'environ 89,6 à 100,3 kDa et 56,1 kDa. L'invention concerne les nouvelles séquences d'ADN, les séquences aminoacides dérivées des protéines correspondantes, et l'utilisation en pathologie et en épidémiologie de ces séquences d'ADN et de ces protéines pour dépister des infections causées par C. pneumoniae, ou leur utilisation comme substances vaccinales.
Birkelund Svend
Christiansen Gunna
Knudsen Katrine
Mygind Per
Pedersen Anna-Sofie Hebsgaard
Birkelund Svend
Christiansen Gunna
Gowling Lafleur Henderson Llp
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