Surface-located campylobacter jejuni polypeptides

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 14/205 (2006.01) A61K 39/02 (2006.01) C07K 16/12 (2006.01) C12N 15/11 (2006.01) G01N 33/569 (2006.01)

Patent

CA 2546873

The present invention relates to surface-located polypeptides of Campylobacter jejuni and their use in vaccination against Campylobacter. The invention furthermore relates to the use in vaccination of polynucleotides, expression vectors, recombinant viruses or recombinant cells expressing these surface- located polypeptides. Moreover, the invention relates to the use of antibodies against the surface-located polypeptides for anti-Campylobacter therapy. Finally, methods for detection of Campylobacter and for identifying anti- Campylobacter agents through the surface-located polypeptides is disclosed.

Cette invention se rapporte à des polypeptides de Campylobacter jejuni localisés en surface et à leur utilisation dans la vaccination contre Campylobacter. Cette invention concerne en outre l'utilisation en vaccination de polynucléotides, de vecteurs d'expression, de virus recombinés ou de cellules recombinées exprimant ces polypeptides localisés en surface. Cette invention concerne également l'utilisation d'anticorps contre ces polypeptides localisés en surface dans la thérapie anti-Campylobacter. Cette invention concerne en outre des procédés pour détecter Campylobacter et pour identifier les agents anti-Campylobacter par l'intermédiaire de ces polypeptides localisés en surface.

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