Surface micromachined microneedles

A - Human Necessities – 61 – M

Patent

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Details

A61M 5/32 (2006.01) A61M 37/00 (2006.01) C12M 3/00 (2006.01)

Patent

CA 2344398

Surface micro-machined micro-needles (32) are formed as single needles (32) or in two-dimensional or three-dimensional micro-needle arrays (30). The micro- needles (32) are fabricated on a substrate (12) which can remain attached to the micro-needles (32) or can be subsequently removed. The two-dimensional or three-dimensional micro-needle arrays (30) can have cross-coupling flow channels (36) which allow for pressure equalization, and balance of fluid flow within the micro-needle arrays (30). Each of the micro-needles (32) has a micro-channel (36) therethrough that provides communication between at least one input port (37) at a proximal end of the micro-needles (32), and at least one output port (39) at an opposite distal end.

La présente invention concerne des micro-aiguilles (32) micro-usinées sur une surface, réalisées sous forme d'aiguilles prises une à une (32) ou montées en matrices bidimensionnelles ou tridimensionnelles (30). Ces micro-aiguilles (32) sont fabriquées sur un substrat (12) qui peut rester solidaire des micro-aiguilles (32) ou peut en être séparé ultérieurement. Ces matrices bidimensionnelles ou tridimensionnelles de micro-aiguilles (30) peuvent comporter des canaux d'écoulement à couplage croisé (36) qui assurent un équilibrage des pressions et de l'écoulement du fluide dans les matrices de micro-aiguilles (30). Chaque micro-aiguille (32) est traversée d'un micro-canal (36) qui met en communication au moins un orifice d'entrée (37) à l'extrémité proximale des micro-aiguilles (32), et au moins un orifice de sortie (39), de l'autre côté, à l'extrémité distale.

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