Surfactant-based gel as an injectable, sustained drug...

A - Human Necessities – 61 – F

Patent

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Details

A61F 2/00 (2006.01) A61K 9/14 (2006.01) A61K 9/50 (2006.01)

Patent

CA 2545800

The present invention provides methods and compositions for the sustained delivery of beneficial agents. In certain embodiments, the invention provides compositions comprising a surfactant, a solvent, and a beneficial agent, wherein upon exposure to a hydrophilic environment, the surfactant and solvent form a viscous gel and the beneficial agents is dispersed or dissolved in the gel. In other embodiments, the invention provides compositions comprising a surfactant, a solvent, a hydrophilic media, and a beneficial agent, wherein the surfactant solvent, and hydrophilic media form a viscous gel and the beneficial agent is dispersed or dissolved in the gel.

L'invention concerne de méthodes et des compositions pour l'administration à effet prolongé d'agents actifs. Dans certains modes de réalisation, les compositions comprennent un tensioactif, un solvant et un agent actif. Dans un environnement hydrophile, le tensioactif et le solvant forment un gel visqueux, dans lequel est dispersé ou dissout l'agent actif. Dans d'autres modes de réalisation, les compositions contiennent un tensioactif, un solvant, un support hydrophile et un agent actif, le tensioactif, le solvant et le support hydrophile formant un gel visqueux, dans lequel est dispersé ou dissout l'agent actif.

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