Surgical prostheses

A - Human Necessities – 61 – L

Patent

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Details

A61L 27/00 (2006.01) A61L 27/48 (2006.01)

Patent

CA 2215283

A biomaterial is provided which is suitable for use in surgery in a human patient. It comprises a coherent layer of non-human collagenous tissue which has been subjected to glutaraldehyde tanning so as to comprise cross-linked collagen fibrils, and a reinforcement of synthetic material embedded within the coherent layer. The synthetic material has structure features for promoting said embedding, the average density of said features being in situ greater than 50 per square centimetre. Improvements are also provided in a method of producing biomaterials by allowing collagenous tissue growth on mesh structures covering support surfaces implanted into host animals. In one aspect a tubular synthetic fibre mesh structure fits loosely over a support rod or tube, and in the other aspect a sheet support is used and the tissue growing around the sheet support is adapted to form a pocket, pouch or envelope of collagenous material.

L'invention a pour objet un biomatériau prévu pour être utilisé en chirurgie sur l'homme. Il comprend une couche cohérente d'un tissu collagène non humain qui a été soumis à un tannage au glutaraldéhyde afin de comprendre des fibriles de collagène non réticulées, et un matériau de renforcement de synthèse encastré dans cette couche cohérente. Le matériau de synthèse présente une structure favorisant cet encastrement, la densité moyenne de cette structure étant in situ supérieure à 50 par centimètre carré. L'invention a également pour objet des améliorations d'un procédé de fabrication de biomatériaux consistant à favoriser la croissance d'un tissu collagène sur des structures en mailles recouvrant des surfaces de support implantées chez l'animal. Selon un aspect, une structure en mailles de fibres synthétiques tubulaires s'insère de manière lâche sur une tige ou un tube de support. Selon un autre aspect, on utilise un support formant feuille et le tissu se développant autour du support formant feuille est adapté pour former une poche, un sac ou une enveloppe de matériau collagène.

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