Surgical stent having micro-geometric patterned surface

Details Surgical stent having micro-geometric patterned surface Surgical stent having micro-geometric patterned surface

A - Human Necessities

61

F

A61F 2/82 (2006.01)

Patent

CA 2555384

A surgical stent having thereon micro-geometric patterned surface and the method of use for inhibiting smooth muscle cell growth into stent lumen are disclosed. The surgical stent has a generally cylindrical stent frame configured to be implanted into a body lumen, and the stent frame has thereon a micro-geometric patterned surface with includes a multiplicity of microgrooves distributed in a pre-determined pattern. Each of the microgrooves has a width in a range of from about 4 to about 40 microns and a depth in a range of from about 4 to 40 microns. The surgical stent can further include drug wells, and the surgical stent can have a biocompatible chemical compound, such as thrombosis inhibitor or cell growth inhibitor, embedded in the microgrooves or drug wells.

L'invention porte sur un stent chirurgical à surface à motifs microgéométriques et sur sa méthode d'utilisation pour inhiber la croissance des cellules des muscles lisses à l'intérieur de la lumière du stent. Ledit stent, de structure sensiblement cylindrique, s'implante dans une lumière corporelle et sa surface comporte des motifs microgéométriques faits de microsillons distribués de manière prédéterminée et d'une largeur d'environ 4 à environ 40 microns et d'une profondeur d'environ 4 à environ 40 microns. Ladite surface peut également présenter des puits à médicaments et être chargée de composés chimiques biocompatibles tels que des inhibiteurs de thrombose ou des inhibiteurs de croissance cellulaire, enfouis dans les microsillons ou les puits à médicaments.

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