Surrogate markers of neuropathic pain

Details Surrogate markers of neuropathic pain Surrogate markers of neuropathic pain

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2556925

The disclosure provides methods and compositions for the evaluation of neuropathic pain and neurotrophic or other activity of a drug or drug candidate. In the disclosed methods, expression of certain gene(s) in tissue extracts from skin biopsies serves as a proxy of a relevant endpoint.

Cette invention concerne des procédés et des compositions servant à l'évaluation de la douleur neuropathique et de l'activité neurotrophique ou autre d'un médicament ou d'un candidat de médicament. Dans ces procédés, l'expression de certain(s) gène(s) dans des extraits de tissu provenant de biopsies de la peau sert d'approximation d'un résultat pertinent.

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