Survivin-derived peptides and use thereof

Details Survivin-derived peptides and use thereof Survivin-derived peptides and use thereof

C - Chemistry, Metallurgy

07

K

C07K 14/47 (2006.01) A61K 38/08 (2006.01) A61K 38/17 (2006.01) A61K 39/00 (2006.01) A61K 49/00 (2006.01) A61P 35/00 (2006.01) C07K 7/06 (2006.01) G01N 33/574 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2513104

MHC Class I-restricted peptides derived from the tumor associated antigen, survivin, which peptides are capable of binding to Class I HLA molecules at a high affinity, capable of eliciting INF-.gamma.-producing cells in a PBL population of a cancer patient and capable of in situ detection of cytotoxic T cells in a tumor tissue, therapeutic and diagnostic composition comprising the peptide and uses thereof.

L'invention concerne des peptides CMH de classe I restreints dérivés de l'antigène associé à une tumeur, la survivine, ces peptides étant capables de se lier à des molécules HLA de classe I avec une affinité élevée, de solliciter des cellules de production INF-?- dans une population de lymphocytes circulants (PBL) d'un patient atteint d'un cancer et de détecter in situ des lymphocytes T cytotoxiques dans un tissu tumoral. L'invention concerne également une composition thérapeutique et diagnostique comprenant le peptide et les utilisations desdits peptides.

Affiliated with

Also associated with

Rating

Survivin-derived peptides and use thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Survivin-derived peptides and use thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Survivin-derived peptides and use thereof will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1452240