Suspension of loteprednol etabonate and tobramycin for...

A - Human Necessities – 61 – K

Patent

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A61K 9/10 (2006.01) A61K 31/56 (2006.01) A61K 31/7036 (2006.01)

Patent

CA 2544139

This invention relates to formulations for topical use comprising antibiotics in combination with anti-inflammatory steroids for treating ophthalmic infections and attendant inflammation. More specifically, this invention relates to pharmaceutical ophthalmic formulations comprising a pH stabilizing amount of tobramycin and the soft steroid loteprednol etabonate.

La présente invention concerne des préparations destinées à une utilisation topique, comprenant des antibiotiques combinés avec des stéroïdes anti-inflammatoires pour traiter des infections ophtalmiques et des infections concomitantes. Plus spécifiquement, cette invention concerne des préparations ophtalmiques pharmaceutiques comprenant une quantité de tobramycine permettant de stabiliser le pH et le stéroïde doux : l'étabonate de loteprednol.

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