Sustainable chick cell line infected with marek's disease virus

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 5/10 (2006.01) A61K 39/255 (2006.01) C07K 14/055 (2006.01) C12N 7/01 (2006.01) C12N 15/01 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2185407

A sustainable cell line of a Marek's disease herpesvirus (MDV) infected chicken cell line derived from chick embryo cells which are chicken helper factor (Chf) negative and which have been treated with N- methyl-N-nitro-N-nitrosoguansidine (MNNG) and then converted with the MDV which is able to infect avians in vivo. The cell line is useful for vaccine production and for determining the characteristics of the MDV under various conditions.

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