A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/08 (2006.01) A61P 37/06 (2006.01)
Patent
CA 2678176
The present invention relates to a rapamycin sustained release delivery system for treatment of diseases responsive to rapamycin. The sustained release delivery system of the invention includes a flowable composition containing rapamycin or a rapamycin derivative, which is capable of providing an implant containing the rapamycin or derivative thereof. The flowable composition may be injected into tissue whereupon it coagulates to become the solid or gel, monolithic implant. The flowable composition includes a biodegradable, thermoplastic polymer, an organic liquid and rapamycin or a rapamycin derivative.
La présente invention concerne un système de libération et de distribution soutenue de rapamycine destiné au traitement de maladies sensibles à la rapamycine. Le système de libération et de distribution soutenue de l'invention comporte une composition liquide contenant de la rapamycine ou un dérivé de rapamycine, qui est capable de fournir un implant contenant de la rapamycine ou un dérivé de celle-ci. La composition liquide peut être injectée dans un tissu, après quoi elle coagule pour devenir l'implant monolithique solide ou gélifié. La composition liquide comporte un polymère thermoplastique biodégradable, un liquide organique et de la rapamycine ou un dérivé de rapamycine.
Dadey Eric
Li Ruihong
Lindemann Christopher M.
Margaron Philippe Maria Clotaire
Goudreau Gage Dubuc
Qlt Inc.
Qlt Usa Inc.
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