Sustained delivery of compstatin analogs from gels

Details Sustained delivery of compstatin analogs from gels Sustained delivery of compstatin analogs from gels

A - Human Necessities

61

K

A61K 9/10 (2006.01) A61K 9/52 (2006.01) A61K 38/08 (2006.01) A61K 38/10 (2006.01) A61P 27/02 (2006.01)

Patent

CA 2701470

The present invention features the sustained delivery of compstatin analog and, optionally, an additional active agent, by release from a macroscopic, gel-like deposit formed by administering a liquid solution containing the compstatin analog to an extravascular location in the body of a mammalian subject such as the vitreous chamber.

La présente invention concerne la distribution soutenue d'analogues de compstatine et, facultativement, d'un agent actif supplémentaire, par libération à partir d'un dépôt macroscopique de type gel, formé par l'administration d'une solution liquide contenant l'analogue de compstatine à un emplacement extravasculaire dans le corps d'un mammifère tel que la chambre vitreuse.

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