C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 17/02 (2006.01) A61K 38/18 (2006.01) A61K 47/42 (2006.01) A61L 27/22 (2006.01) A61P 9/10 (2006.01) C07K 7/08 (2006.01) C07K 14/49 (2006.01) C07K 17/00 (2006.01)
Patent
CA 2592292
The present invention is directed to a therapeutic composition in which human PDGF is bound directly to peptides that self assemble into a biologically compatible gel. When implanted in a patient~s body, the composition provides for the slow, sustained release of PDGF. The composition will be especially useful in treating patients who have undergone a myocardial infarction.
La présente invention concerne une composition thérapeutique dans laquelle du PDGF humain est lié directement à des peptides qui s'autoassemblent dans un gel biologiquement compatible. Une fois implantée dans le corps d'un patient, la composition assure la libération lente et prolongée du PDGF. Cette composition est tout particulièrement utile pour traiter des patients qui ont souffert d'un infarctus du myocarde.
Hsieh Patrick
Lee Richard T.
Smart & Biggar
The Brigham And Women's Hospital Inc.
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