Sustained release capsule or tablet formulation

Details Sustained release capsule or tablet formulation Sustained release capsule or tablet formulation

A - Human Necessities

61

K

167/229

A61K 9/52 (2006.01) A61K 9/14 (2006.01) A61K 9/20 (2006.01) A61K 9/22 (2006.01) A61K 31/44 (2006.01) A61K 47/48 (2006.01)

Patent

CA 1288049

- 17 - ABSTRACT SUSTAINED RELEASE CAPSULE OR TABLET FORMULATION A sustained release capsule or tablet formulation suitable for once-daily administration comprises an adsorbate of a mixture of a pharmaceutically useful dihydropyridine and a polyvinylpyrrolidone having an average molecular weight greater than 55,000 adsorbed on a cross-linked polyvinylpyrrolidone and blended with a polymer or mixture of polymers which gel in the presence of water, the amount of said polymer or polymers being effective to produce the desired sustained release effect.

528749

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