A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/09 (2006.01) A61K 38/00 (2006.01) A61P 5/28 (2006.01) A61P 15/08 (2006.01) A61P 15/16 (2006.01) A61P 15/18 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2568641
A sustained release apparatus including at least one sustained release mini- implant or pellet; the or each mini-implant or pellet including: a sustained release support material; and a pharmaceutical composition including a Luteinising Hormone Releasing Hormone (HLRH) agonist and/or antagonist component the size and/or number and/or payload of mini-implant(s) or pellet(s) providing, release of LHRH agonist and/or antagonist at, or above, a desired threshold level for treatment of a selected indication, the apparatus providing approximately zero order release of the LHRH agonist and/or antagonist.
L'invention concerne un appareil de libération prolongée comprenant au moins un mini-implant ou granule à libération prolongée, lequel comprend : un matériau de support à libération prolongée ; et une composition pharmaceutique comprenant un composant agoniste et/ou antagoniste de lutéolibérine (HLRH) présentant la taille et/ou le nombre et/ou la charge utile de mini-implant(s) ou granule(s) assurant la libération de l'agoniste et/ou l'antagoniste de LHRH à, ou dépassant, un niveau seuil souhaité pour le traitement d'une choisie indication, cet appareil produisant une libération environ d'ordre zéro de l'agoniste et/ou l'antagoniste de LHRH.
Brandon Malcolm
Martinod Serge
Gowling Lafleur Henderson Llp
Smart Drug Systems Inc
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