Sustained release composition

A - Human Necessities – 61 – K

Patent

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Details

A61K 38/09 (2006.01) A61K 9/16 (2006.01) A61K 9/70 (2006.01) A61K 31/19 (2006.01) A61K 31/40 (2006.01) A61K 47/34 (2006.01)

Patent

CA 2183620

This invention provides a sustained release composition comprising a PLGA matrix, a bioactive agent, and a quaternary ammonium surfactant, in which the release profile of the bioactive agent from the PLGA matrix is controlled by the concentration of the quaternary ammonium surfactant.

Cette invention concerne une composition à libération prolongée comprenant une matrice de PLGA, un agent bioactif et un surfactant d'ammonium quaternaire, composition dans laquelle le profil de libération de l'agent bioactif à partir de la matrice de PLGA est commandé par la concentration du surfactant d'ammonium quaternaire.

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