Sustained release delivery of active agents to treat...

A - Human Necessities – 61 – K

Patent

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A61K 31/5575 (2006.01) A61P 27/02 (2006.01) A61P 27/06 (2006.01)

Patent

CA 2722971

The methods described herein provide treatment of glaucoma, ocular hypertension, and elevated intraocular pressure with latanoprost or other therapeutic agent(s). Implant devices for insertion into a punctum of a patient provide sustained release of latanoprost or other therapeutic agent(s) that is maintained for 7, 14, 21, 30, 45, 60, or 90 days or more, thus avoiding patient noncompliance and reducing or lowering adverse events associated with eye drop administration of latanoprost or other therapeutic agent(s) and other therapeutic agent(s).

Cette invention concerne des méthodes de traitement du glaucome, de lhypertension oculaire et de la pression intra-oculaire élevée avec du Latanoprost or un ou des autres agents thérapeutiques. Des dispositifs dimplant destinés à être insérés dans un orifice chez un patient permettent une libération prolongée du Latanoprost ou dun autre ou dautres agents thérapeutiques qui est maintenue pendant 7, 14, 21, 30, 45, 60 ou 90 jours ou plus, évitant ainsi la non-observance du patient et réduisant ou diminuant les effets indésirables associés à ladministration de gouttes oculaires de Latanoprost ou dun autre dautres agents thérapeutiques.

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