Sustained release drug-resin complexes

Details Sustained release drug-resin complexes Sustained release drug-resin complexes

A - Human Necessities

61

K

167/161

A61K 47/48 (2006.01) A61K 9/18 (2006.01) A61K 9/50 (2006.01) A61K 9/52 (2006.01)

Patent

CA 2001859

Disclosed are oral pharmaceutical preparations which comprise a pharmacologically active drug bound to small particles of an ion- exchange resin to provide a drug-resin complex having a drug content above a specified value. The drug-resin complex is subsequently coated with a water-permeable diffusion barrier coating that is insoluble in gastrointestinal fluids thereby providing a controllable sustained release of drug under conditions encountered in the gastrointestinal tract.

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