Sustained release formulation

A - Human Necessities – 61 – K

Patent

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Details

A61K 38/27 (2006.01) A61K 33/30 (2006.01) A61K 38/18 (2006.01) A61K 38/28 (2006.01) A61K 47/26 (2006.01)

Patent

CA 2448218

A composition comprises a protein, a polyiol, and a metal. The protein is stabilized by the polyol and the metal, and is protected from denaturing when in contact with an organic solvent. The polyol may be a hydrocarbon containing two or more hydroxyl groups (-OH) bonded to carbon. The metal may be divalent.

L'invention concerne une composition comprenant une protéine, un polyol et un métal. La protéine est stabilisée par le polyol et le métal, et protégée contre la dénaturation lorsqu'elle est en contact avec un solvant organique. Le polyol peut être un hydrocarbure contenant deux au plusieurs groupes hydroxyles (-OH) liés au carbone. Le métal peut être divalent.

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