Sustained-release formulation of a cyclooxygenase-2 inhibitor

Details Sustained-release formulation of a cyclooxygenase-2 inhibitor Sustained-release formulation of a cyclooxygenase-2 inhibitor

A - Human Necessities

61

K

A61K 31/415 (2006.01) A61K 9/20 (2006.01) A61K 9/24 (2006.01) A61K 9/50 (2006.01) A61K 31/135 (2006.01) A61K 31/341 (2006.01) A61K 31/42 (2006.01) A61K 31/44 (2006.01) A61K 45/06 (2006.01) A61P 19/02 (2006.01) A61K 9/16 (2006.01)

Patent

CA 2394222

There is provided an orally deliverable pharmaceutical composition comprising a selective cyclooxygenase-2 inhibitory drug of low water solubility such as celecoxib and a release-extending polymer. The composition is useful in treatment of cyclooxygenase-2 mediated conditions and disorders by once-a-day administration.

L'invention concerne une composition pharmaceutique pouvant être administrée par voie orale contenant un médicament inhibiteur sélectif de cyclo-oxygénase-2 de faible solubilité dans l'eau tel qu'un celecoxib et un polymère prolongeant la libération. La composition est utile dans le traitement d'états et de troubles induits par la cyclo-oxygénase-2 par administration une fois par jour.

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