Sustained release formulations of aromatase inhibitors

Details Sustained release formulations of aromatase inhibitors Sustained release formulations of aromatase inhibitors

A - Human Necessities

61

K

A61K 9/14 (2006.01) A61K 31/00 (2006.01)

Patent

CA 2654113

The invention discloses microparticles or nanoparticles comprising an aromatase inhibitor, preferably letrozole, in a polymeric matrix, preferably poly(lactide-co-glycolide) glucose. The invention also discloses sustained release formulations containing said microparticles and the use of said formulations in treating cancer.

La présente invention concerne des microparticules ou des nanoparticules contenant un inhibiteur de l'aromatase, de préférence le létrozole, dans une matrice polymérique, de préférence le poly(lactide-co-glycolide)glucose. L'invention concerne également des formulations à libération prolongée contenant lesdites microparticules et l'utilisation desdites formulations dans le traitement du cancer.

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