Sustained-release granular preparation

A - Human Necessities – 61 – K

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A61K 9/36 (2006.01) A61K 9/16 (2006.01) A61K 9/50 (2006.01) A61K 47/00 (2006.01)

Patent

CA 1154675

SUSTAINED-RELEASE GRANULAR PREPARATIONS ABSTRACT OF THE DISCLOSURE A favourable sustained-releasing property is given to granular preparations by incorporating therein at least one of C16-C18 saturated fatty acid and/or metal salts thereof at a rate of 10-50 % of the total weight of the dosage form. The disclosed dosage form releases the active ingredient both in a low pH region of the stomach and in a high pH region of the intestine at an appropriate rate.

377961

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