Sustained release of antiinfectives

A - Human Necessities – 61 – K

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

A61K 9/127 (2006.01) A61K 47/44 (2006.01)

Patent

CA 2614764

Provided are lipid antiinfective formulations substantially free of anionic lipids with a lipid to antiinfective ratio is about 1 :1 to about 4:1, and a mean average diameter of less than about 1 µm. Also provided is a method of preparing a lipid antiinfective formulation comprising an infusion process. Also provided are lipid antiinfective formulations wherein the lipid to drug ratio is about 1 : 1 or less, about 0.75:1 or less, or about 0.50:1 or less prepared by an in line fusion process. The present invention also relates to a method of treating a patient with a pulmonary infection comprising administering to the patient a therapeutically effective amount of a lipid antiinfective formulation of the present invention. The present invention also relates to a method of treating a patient for cystic fibrosis comprising administering to the patient a therapeutically effective amount of a lipid antiinfective formulation of the present invention.

L'invention concerne des formulations anti-infectieuses lipidiques sensiblement exemptes de lipides anioniques, qui présentent un rapport du lipide à la substance anti-infectieuse d'environ 1:1 à environ 4:1 et un diamètre moyen inférieur à environ 1 ?m. L'invention concerne également une méthode de préparation d'une formulation anti-infectieuse lipidique comprenant un procédé d'infusion. Elle concerne aussi des formulations anti-infectieuses lipidiques dans lesquelles le rapport du lipide au médicament est d'au plus environ 1:1, d'au plus environ 0,75:1 ou d'au plus environ 0,50:1, et qui sont préparées par un procédé de fusion en ligne. L'invention concerne en outre une méthode de traitement d'un patient atteint d'une infection pulmonaire, qui consiste à administrer au patient une quantité thérapeutiquement efficace d'une formulation anti-infectieuse lipidique de l'invention. L'invention concerne enfin une méthode de traitement d'un patient atteint de mucoviscidose, qui consiste à administrer au patient une quantité thérapeutiquement efficace d'une formulation anti-infectieuse lipidique de l'invention.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Sustained release of antiinfectives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Sustained release of antiinfectives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Sustained release of antiinfectives will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1590897

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.